Stroke Information What Is Stroke What Causes Stroke What causes stroke? Stroke can happen to anyone, of any age and at any time. There are, however, a number of warning signs that will increase the likelihood of an individual being affected by stroke. High blood pressure is the most important and others include a previous stroke or transient ischemic attack (TIA), diabetes, high cholesterol, cigarette smoking and atrial fibrillation. Doctors refer to these conditions as ‘modifiable’ risk factors, as they can usually be controlled, treated or changed. Visit our raising awareness section for more information on how simple lifestyle changes can reduce the likelihood of you or your loved one experiencing stroke.